People who are ‘night owls’ face greater risk of diabetes: Study

Are you an early bird or a night owl? Our sleep cycles could influence our risk of diseases, such as type 2 diabetes and heart disease, said a new study published in Experimental Physiology.

As sleep cycles cause metabolic differences and alter our body’s preference for energy sources, those who stay up later have a reduced ability to use fat for energy, meaning fats may build-up in the body and increase risk for type 2 diabetes and cardiovascular disease, said the study

The metabolic differences relate to how well each group can use insulin to promote glucose uptake by the cells for storage and energy use. People who are ‘early birds’ or individuals who prefer to be active in the morning rely more on fat as an energy source and are more active during the day with higher levels of aerobic fitness than ‘night owls’.

On the other hand, ‘night owls’ who prefer to be active later in the day and night use less fat for energy at rest and during exercise, found the study

Researchers from Rutgers University, New Jersey classified participants (n=51) into two groups (early and late) based on their ‘chronotype’ – our natural propensity to seek activity and sleep at different times. They used advanced imaging to monitor body vitals as well as insulin sensitivity and breath samples to measure fat and carbohydrate metabolism.

After monitoring them for a week, they were tested while at rest before completing two 15-minute bouts of exercise: one moderate and one high intensity session on a treadmill. Aerobic fitness levels were tested through an incline challenge where the incline was raised 2.5% every two minutes until the participant reached a point of exhaustion.

Researchers found that early birds use more fat for energy at both rest and during exercise than night owls. Early birds were also more insulin sensitive. Night owls, on the other hand, are insulin resistant, meaning their bodies require more insulin to lower blood glucose levels, and their bodies favoured carbohydrates as an energy source over fats.

This group’s impaired ability to respond to insulin to promote fuel use can be harmful as it indicates a greater risk of type 2 diabetes and/or heart disease. The cause for this shift in metabolic preference between early birds and night owls is yet unknown and needs further investigation.

Senior author Professor Steven Malin of Rutgers University said: “A sensitive or impaired ability to respond to the insulin hormone has major implications for our health. This observation advances our understanding of how our body’s circadian rhythms impact our health. ”

The study also found that early birds are more physically active and have higher fitness levels than night owls.

Heart attack prevention lags for people with stroke, peripheral artery disease: Study

Preventon of heart attack efforts are found to be unequal in patients who usually reach the stage after several cardovascular diseases and stroke, according to a recent study, whch advocated early treatment methods to ward off such eventualites among patients.

The findings were presented at the American Heart Association’s Quality of Care & Outcomes Research Scientific Sessions 2020, which had its virtual conference, May 15-16, at a global level exchangng the latest advances in quality of care and outcomes research in cardiovascular disease and stroke for researchers, health care professionals and policymakers.

Researchers found that patients with peripheral artery disease or stroke were less likely than those with coronary artery disease to receive proper treatment to prevent heart attack. All three are types of atherosclerotic cardiovascular disease — coronary artery disease, stroke and peripheral artery disease — lead to heart attack. The 2016 AHA/ACC guidelines recommend aspirin for patients with symptomatic peripheral artery disease, while 2018 guidelines undeerscore that statin therapy reduces the risk of atherosclerotic events.

Heart Diseases

Worldwide, a major contributor to cardiovascular disease is atherosclerosis, which occurs when cholesterol, fat and inflammatory cells build up and form plaque that blocks the arteries and impedes blood flow. Depending on its location, atherosclerosis increases the risk for the three serious conditions. Coronary artery disease results from damaged heart arteries. A common type of stroke occurs when clogged arteries block blood flow to brain. Peripheral artery disease results from damaged arteries in the extremities such as legs, and can lead to amputation.

“Our study highlights the need for public health campaigns to direct equal attention to all three major forms of atherosclerotic cardiovascular disease,” said senior study author Erin Michos, from the Johns Hopkins University School of Medicine in Baltimore. “We need to generate awareness among both clinicians and patients that all of these diseases should be treated with aggressive secondary preventive medications, including aspirin and statins, regardless of whether people have heart disease or not.”

Guidelines to treat all 3 cardiovascular diseases alike

Since atherosclerosis can affect arteries in more than one part, guidelines are to treat coronary artery disease, stroke and peripheral artery disease similarly with lifestyle changes and medication, including statins to lower cholesterol levels and aspirin to prevent blood clots.

Lifestyle changes include eating a healthy diet, being physically active, quitting smoking, controlling high cholesterol, controlling high blood pressure, treating high blood sugar and losing weight. If people with stroke and peripheral artery disease received the same treatments prescribed for those with coronary artery disease, the results would be encouragng, said the study.

For the study, researchers compared more than 14,000 U.S. adults enrolled in the 2006-2015 Medical Expenditure Panel Survey, and slightly more than half of the patients were men, the average age was 65, and all had either coronary artery disease, stroke or peripheral artery disease. These individuals were representative of nearly 16 million U.S. adults living with one of the three forms of atherosclerotic cardiovascular disease.

“Our study highlights a missed opportunity for implementing life-saving preventive medications among these high-risk individuals,” Michos said. “Peripheral artery disease and stroke should generally be treated with the same secondary prevention medications as coronary artery disease.”

Compared to participants with coronary artery disease:

  1. Participants with peripheral artery disease were twice more likely to report no statin use and three times more likely to report no aspirin use;
  2. People with peripheral artery disease had the highest, annual, total out-of-pocket expenditures among the three atherosclerotic conditions;
  3. Participants with stroke were more than twice as likely to report no statin or aspirin use; and
  4. Those with stroke were more likely to report poor patient-provider communication, poor health care satisfaction and more emergency room visits.

 

Obesity in Children on Rise

Junk Food is a term used for food containing high levels of calories from sugar or fat with little fiber, protein, vitamins or minerals. These foods lead to a rapid increase in blood sugar levels (high glycemic index) which forces the body to produce high levels of insulin to counter the rising blood sugar.

As reported by Indian Council of Medical Research (ICMR), development of obesity is multi-factorial and eating of junk and processed food is one of them. Childhood obesity is a risk factor of developing heart diseases and diabetes in later life.

The results available from 15 States/UTs of an ongoing ICMR India Diabetes (ICMR-INDIAB) Study on the prevalence of diabetes indicate overall prevalence of Diabetes varying from 4% to 13%. According to the Report of National Commission on Macroeconomics and Health, there were 641 lakh cases of Cardiovascular Diseases (CVDs) in India in the year 2015.

Ministry of Women and Child Development had constituted a Working Group on addressing consumption of foods High in Fat, Salt and Sugar (HFSS) and promotion of healthy snacks in schools of India, which has given its report.

The Food Safety and Standards Authority of India (FSSAI) constituted an Expert Group on Salt, Sugar and Fat. The Expert Group prepared a draft report on consumption of these items and its health impacts among Indian population and recommendations on healthy dietary intake of these items. While preparing the above report, Expert Group has considered WHO guidelines on ‘Sugar Intake for Adults and Children regarding the adverse impact of high sugar in foods.

ICMR, National Institute of Nutrition (NIN) and other institutions carry out research and studies related to food and healthy diet. Apart from this, the consumers are made aware of food safety through consumer awareness programmes launched jointly by the Department of Consumer Affairs and the Food Safety and Standards Authority of India (FSSAI) which also includes advertisements in different media, campaigns, educational booklets, information on FSSAI website and Mass awareness campaigns.

The Minister of State (Health and Family Welfare), Smt Anupriya Patel stated this in a written reply in the Lok Sabha here today.