Mother’s ultra-processed food intake linked to obesity risk in children; Unlikely during peripregnancy

A mother’s consumption of ultra-processed foods appears to be linked to an increased risk of overweight or obesity in her offspring, irrespective of other lifestyle risk factors, suggests a US study.

Researchers suggest that mothers might benefit from limiting their intake of ultra-processed foods, and that dietary guidelines should be refined and financial and social barriers removed to improve nutrition for women of child bearing age and reduce childhood obesity.

According to the World Health Organization, 39 million children were overweight or obese in 2020, leading to increased risks of heart disease, diabetes, cancers, and early death.

Ultra-processed foods, such as packaged baked goods and snacks, fizzy drinks and sugary cereals, are commonly found in modern Western style diets and are associated with weight gain in adults. But it’s unclear whether there’s a link between a mother’s consumption of ultra-processed foods and her offspring’s body weight.

To explore this further, the researchers drew on data for 19,958 children born to 14,553 mothers (45% boys, aged 7-17 years at study enrollment) from the Nurses’ Health Study II (NHS II) and the Growing Up Today Study (GUTS I and II) in the United States.

pregnant lady

pregnant lady/Commons.wikimedia.org

The NHS II is an ongoing study tracking the health and lifestyles of 116,429 US female registered nurses aged 25-42 in 1989. From 1991, participants reported what they ate and drank, using validated food frequency questionnaires every four years.

The GUTS I study began in 1996 when 16,882 children (aged 8-15 years) of NHS II participants completed an initial health and lifestyle questionnaire and were monitored every year between 1997 and 2001, and every two years thereafter.

In 2004, 10,918 children (aged 7-17 years) of NHS II participants joined the extended GUTS II study and were followed up in 2006, 2008, and 2011, and every two years thereafter.

A range of other potentially influential factors, known to be strongly correlated with childhood obesity, were also taken into account. These included mother’s weight (BMI), physical activity, smoking, living status (with partner or not), and partner’s education, as well as children’s ultra-processed food consumption, physical activity, and sedentary time.

Overall, 2471 (12%) children developed overweight or obesity during an average follow-up period of 4 years.

The results show that a mother’s ultra-processed food consumption was associated with an increased risk of overweight or obesity in her offspring. For example, a 26% higher risk was seen in the group with the highest maternal ultra-processed food consumption (12.1 servings/day) versus the lowest consumption group (3.4 servings/day).

In a separate analysis of 2790 mothers and 2925 children with information on diet from 3 months pre-conception to delivery (peripregnancy), the researchers found that peripregnancy ultra-processed food intake was not significantly associated with an increased risk of offspring overweight or obesity.

This is an observational study, so can’t establish cause and the researchers acknowledge that some of the observed risk may be due to other unmeasured factors, and that self-reported diet and weight measures might be subject to misreporting.

Other important limitations include the fact that some offspring participants were lost to follow-up, which resulted in a few of the analyses being underpowered, particularly those related to peripregnancy intake, and that mothers were predominantly white and from similar social and economic backgrounds, so the results may not apply to other groups.

Nevertheless, the study used data from several large ongoing studies with detailed dietary assessments over a relatively long period, and further analysis produced consistent associations, suggesting that the results are robust.

The researchers suggest no clear mechanism underlying these associations and say the area warrants further investigation.

Nevertheless, these data “support the importance of refining dietary recommendations and the development of programs to improve nutrition for women of reproductive age to promote offspring health,” they conclude.

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Mass media linked to childhood obesity

A task force from the European Academy of Paediatrics and the European Childhood Obesity Group has found evidence of a strong link between obesity levels across European countries and childhood media exposure. The experts’ review is published in Acta Paediatrica.

The findings indicate that parents and society need a better understanding of the influence of social media on dietary habits. In addition, health policies in Europe must take account of the range of mass media influences that promote the development of childhood obesity.

“Parents should limit TV viewing and the use of computers and similar devices to no more than 1.5 hours a day and only if the child is older than four years of age. Moreover, paediatricians should Inform parents about the general risk that mass media use poses to their children’s cognitive and physical development,” said senior author Dr. Adamos Hadjipanayis, of the European Academy of Paediatrics.

Is childhood obesity a psychological disorder?

A team of researchers, including senior investigator, Bradley Peterson, MD, director of the Institute for the Developing Mind at Children’s Hospital Los Angeles, used fMRI to investigate neural responses to food cues in overweight compared with lean adolescents. The team observed that food stimuli activated regions of the brain associated with reward and emotion in all groups. However, adolescents at an increasing risk for obesity had progressively less neural activity in circuits of the brain that support self-regulation and attention.

“This study establishes that risk for obesity isn’t driven exclusively by the absence or presence of urges to eat high-calorie foods, but also, and perhaps most importantly, by the ability to control those urges,” said Peterson, who is also a professor at the Keck School of Medicine at the University of Southern California.

The public health implications of childhood obesity are staggering. More than half of all adolescents in the U.S. are either overweight or obese. Children of overweight parents (2/3 of adults in the U.S.) already are or are likely to become overweight. Since excess weight has been linked to a myriad of health issues shown to limit human potential and add to the skyrocketing cost of healthcare, researchers are actively seeking novel approaches to understand better the causes of obesity and alter its trajectory. This study, recently reported in the journal NeuroImage, may offer such an approach.

“We wanted to use brain imaging to investigate a key question in obesity science: why do some people become obese, while others don’t?” said Susan Carnell, PhD, assistant professor of Child & Adolescent Psychiatry, Johns Hopkins University School of Medicine and first author on the study.

Of the 36 adolescents (ages 14 to 19 years) enrolled in the study, 10 were overweight/obese, 16 were lean but considered at high risk for obesity because they had overweight/obese mothers and 10 were lean/low risk since they had lean mothers. The adolescents underwent brain scanning using fMRI, while they viewed words that described high-fat foods, low-fat foods and non-food items. Then they rated their appetite in response to each word stimulus. Following the activity, all participants were offered a buffet that included low- and high-calorie foods — to relate participants test responses to real-world behavior.

The investigators observed that after viewing food-related words, brain circuits that support reward and emotion were stimulated in all participants. In adolescents who were obese or who were lean but at high familial risk for obesity, they observed less activation in attention and self-regulation circuits.

Brain circuits that support attention and self-regulation showed the greatest activation in lean/low-risk adolescents, less activity in lean/high-risk participants and least activation in the overweight/obese group. Also, real world relevance mirrored fMRI findings — food intake at the buffet was greatest in the overweight/obese participants, followed by the lean/high-risk adolescents and lowest in the lean/low-risk group.

“These findings suggest that interventions designed to stimulate the self-regulatory system in adolescents may provide a new approach for treating and preventing obesity,” said Peterson.

Obesity in Children on Rise

Junk Food is a term used for food containing high levels of calories from sugar or fat with little fiber, protein, vitamins or minerals. These foods lead to a rapid increase in blood sugar levels (high glycemic index) which forces the body to produce high levels of insulin to counter the rising blood sugar.

As reported by Indian Council of Medical Research (ICMR), development of obesity is multi-factorial and eating of junk and processed food is one of them. Childhood obesity is a risk factor of developing heart diseases and diabetes in later life.

The results available from 15 States/UTs of an ongoing ICMR India Diabetes (ICMR-INDIAB) Study on the prevalence of diabetes indicate overall prevalence of Diabetes varying from 4% to 13%. According to the Report of National Commission on Macroeconomics and Health, there were 641 lakh cases of Cardiovascular Diseases (CVDs) in India in the year 2015.

Ministry of Women and Child Development had constituted a Working Group on addressing consumption of foods High in Fat, Salt and Sugar (HFSS) and promotion of healthy snacks in schools of India, which has given its report.

The Food Safety and Standards Authority of India (FSSAI) constituted an Expert Group on Salt, Sugar and Fat. The Expert Group prepared a draft report on consumption of these items and its health impacts among Indian population and recommendations on healthy dietary intake of these items. While preparing the above report, Expert Group has considered WHO guidelines on ‘Sugar Intake for Adults and Children regarding the adverse impact of high sugar in foods.

ICMR, National Institute of Nutrition (NIN) and other institutions carry out research and studies related to food and healthy diet. Apart from this, the consumers are made aware of food safety through consumer awareness programmes launched jointly by the Department of Consumer Affairs and the Food Safety and Standards Authority of India (FSSAI) which also includes advertisements in different media, campaigns, educational booklets, information on FSSAI website and Mass awareness campaigns.

The Minister of State (Health and Family Welfare), Smt Anupriya Patel stated this in a written reply in the Lok Sabha here today.