Vitamin B12 Deficiency Sensor Developed to Detect Dementia, Alzheimer Disease in Minutes

In old-age, the frequent occurrence of B12 deficiency could lead to dementia and even Alzheimer’s disease as the body metabolism fails to absorb the vitamin from the diet, requiring an early medical intervention.

To help detect B12 deficieny early, Australia’s University of Adelaide researchers have developed a first of its kind optical sensor using a technique called Raman spectroscopy that can detect vitamin B12 in diluted human blood – a first step towards a low-cost, portable, broadscale vitamin B12 deficiency test.

The sensor, still at proof-of-concept stage, has wide-reaching potential applications. It enables doctors in tracking vitamin B12 levels in high-risk patients and provide an early intervention – to top up immediately vitamin B12 levels when low. Current tests are lengthy and costly too.

Scientists in the ARC Centre of Excellence for Nanoscale BioPhotonics (CNBP), the Institute for Photonics and Advanced Sensing, and the Schools of Physical Sciences and Medicine, in their presentation today at an international biophotonics conference in Adelaide – the inaugural SPIE BioPhotonics Australasia conference — revealed the new sensor.

“Vitamin B12 deficiency has been shown to be a potential modifiable risk factor for dementia and Alzheimer’s disease and is associated with cognitive decline,” says Dr Georgios Tsiminis, Research Fellow at the University of Adelaide.

“Our sensor is an early first step towards a point-of-care solution for measuring and tracking B12 in healthy ageing adults. This would allow doctors to monitor B12 levels and intervene.”

"Currently our device could not aid in diagnosing vitamin B12 deficiency in a general practice setting… We believe this is a very promising first step towards achieving this goal," she said.

The optical sensor measures B12 in human blood in less than a minute and requires minimum preparation. This is the first demonstration of vitamin B12 being measured in human blood serum without the need for a full lab tests.

The sensor uses an optical measuring technique called Raman spectroscopy which produces a unique optical fingerprint of a target molecule, in this case vitamin B12.


Suu Kyi Calls on President Mukherjee

The State Counsellor of Myanmar, Ms. Aung San Suu Kyi calling on President Pranab Mukherjee, at Rashtrapati Bhavan, in New Delhi on Tuesday, October 18, 2016

Myanmar leader Aung San Suu Kyi, the State Counsellor of the Republic of Myanmar called on President Pranab Mukherjee at Rashtrapati Bhavan on Tuesday, (October 18, 2016).

Welcoming Aung San Suu Kyi on her first State Visit to India, the President said that India and Myanmar are close neighbours and have a good long standing relationship with each other. During the visit of the President of Myanmar in August this year, fruitful discussions were held and four important agreements were signed between the two countries.

The President congratulated Aung San Suu Kyi on her landmark victory in the General Elections held in November, 2015. The President said that India appreciates the spirit with which the people of Myanmar have responded in the General Elections and the manner in which the whole process of elections has been steered. He said that he was happy that the process of democratization was being strengthened in Myanmar.

India will extend all help to Myanmar in this phase of transition in order to set up democratic institutions for ensuring stability in the country. He wished Myanmar all success in establishing a strong democracy. He stated that Myanmar’s transition to full democracy will take time to achieve and India stands by Myanmar in this process.

The President said that India will soon commence work on restoring two old temples and inscriptions of King Mindon and Bay Gyi Daw in Bodh Gaya as requested by the Government of Myanmar. He said that this task will be undertaken by the Archeological Survey of India with financial support from Government of India.

Daw Aung San Suu Kyi reciprocated the President’s sentiments and said that India and Myanmar have much in common. She stated that change does not happen easily and Myanmar has to go about the process of transition in a cautious manner. Myanmar seeks the cooperation and support of India as its people look forward to progress and change for the betterment of their lives.

RV College of Engineering to Conduct Uranium-Related Research in Karnataka

Board of Research in Nuclear Science has granted Rs.25 lakh to Bangalore=based RV College of Engineering for conducting research on spatial distribution of uranium and its impact on water in five districts of Karnataka.

The grant for three years enables Bangalore’s No.1 engineering college to undertake the project entitled “Spatial distribution of Uranium and associated water quality parameters in Bangalore, Bangalore Rural, Ramanagara, Chikkaballapura and Kolar district in Karnataka” spanning over three years.

The project will be undertaken by Dr. M. Rajalakshmi, Dr. Sham Aan and Dr. R. Suresh of the Department of Chemical Engineering, R. V. College of Engineering. The funding agency, Board of Research in Nuclear Sciences (BRNS), is part of the country’s Department of Atomic Energy.

Cabinet Approves MoU between India, EU on Water

The Union Cabinet under PM Narendra Modi has given its approval for the signing of MoU between India and European Union in the field of water resources.

The MoU envisages strengthening the technological, scientific and management capabilities of India and the European Union in the field of water management on the basis of equality, reciprocity and mutual benefit. It provides technical exchange on water issues, including on integrated water resource management plans within river basins and through study visits.

The MoU aims to identify key environmental issues and approaches to sustainable development where exchange of experiences and cooperation could be mutually beneficial to strengthen and further develop cooperation between India and the European Union in the field of water management.

The pact envisions a more sustainable management of water resources in India with an objective of tackling the challenges posed by water management in the context of growing population, competing water demands and a changing climate. A Joint Working Group shall be formed to monitor the activities to be carried out in fulfillment of the MoU.

The Ministry of Water Resources, River Development and Ganga Rejuvenation has been envisaging bilateral cooperation with other countries in water resources development and management through sharing of policy and technical expertise, conducting of training courses, workshops, scientific and technical symposia, exchange of experts and study tours.

Keeping in view the success of the European Union in distribution of water resources, water pricing, water use efficiency by encouraging the changes in agricultural practices necessary to protect water resources and quality, such as switching to less water-demanding crops, etc., it has been decided to have an agreement with Israel to benefit from their experience and expertise.

The EU States have adopted water pricing policies to provide adequate incentives for users to use water resources efficiently thereby contributing to environmental objectives.

Cabinet Okays MoU with African Asian Rural Development Organization

The Union Cabinet chaired by Prime Minister Narendra Modi has given its approval to the signing of a Memorandum of Understanding (MoU) between India and the African Asian Rural Development Organization (AARDO) for capacity building programmes in the field of rural development.

The MoU for the triennium 2015 – 2017 is being signed under which capacity building programmes for AARDO member countries will be organized every year during the triennium at various Institutions of Excellence in India such as National Institute of Rural Development & Panchayati Raj (NIRD & PR), institutions governed by the Indian Council of Agricultural Research (ICAR), Indian Institute of Management (IIM) and others. The duration of each training programme shall be of two to three weeks. The Post Graduate Diploma in Rural Development Management Course at NIRD & PR under this scheme is for one year.

The AARDO, which has its headquarters in New Delhi, is an autonomous, inter-Governmental organization established in 1962 with the objective of promoting cooperation among the countries of the African – Asian Region in the direction of eradicating thirst, hunger, illiteracy, disease and poverty in the region.

India is one of the Founder Members of the Organization and is the largest contributor in terms of membership contribution of US$ 141,100 apart from contributing by way of providing 70 fully paid training scholarships for Human Resource Development Programme under the Indian Technical & Economic Cooperation Programme (ITEC) to the Organization.

India has also provided a building for housing the AARDO Secretariat in Delhi and considerable financial assistance is given to AARDO for maintenance of the building. AARDO currently has 31 countries of the African – Asian Region under its fold.

Since the year 2009, India is continuing to provide an Additional Contribution of US$ 600,000 to AARDO for each triennium 2009-2011 to expand its scale and scope of the Capacity Building Programmes of AARDO for the benefit of Member Countries.

Promote Indian Entrepreneurs Abroad in Global Industries: Minister

Piyush Goyal, Union Minister of State (IC) for Power, Coal, New & Renewable Energy and Mines, said that Indian entrepreneurship needs to be promoted in global electrical industry.

While speaking at Light India Exhibition 2016, Goyal said, “We welcome technology from all around the world but at the end of the day, we would like to strengthen our Indian hands. I am happy to have imports come in, if we are at level playing field. But if we find that other countries are dumping goods into India, certainly that is not welcome in the country.”

Appreciating new and innovative concepts like solar street lights at the exhibition, Goyal stated, “I can actually imagine putting up not less than 10 or 15 million solar street lights, particularly in rural areas.”

Goyal also emphasized on the fact that modalities like cost, battery life, newer technology, process monitoring etc are yet to be work out. Referring to the disruptive economy, the Minister asked Industry to reorient their price structure. He urged the industry to participate in LED street programme aggressively.

Talking about Bureau of Indian Standards, the minister said that the standards need to be better monitored in the imported electrical products.

ONGC Videsh to Acquire 11% Stake in JSC Vankorneft

India’s Cabinet Committee on Economic Affairs, chaired by Prime Minister Narendra Modi, has given its approval to an cquisition by ONGC Videsh Limited (OVL) for 11% stake in JSC Vankorneft from M/s Rosneft Oil Company (Rosneft), the National Oil Company (NOC) of Russian Federation (Russia). Rosneft operates Vankor fields, with Vankorneft, its wholly owned subsidiary.

OVL will be paying an amount of US$ 930 million for acquiring 11% stake in Vankorneft.

The acquisition of stake in Vankorneft will provide 3.2 Million Metric Ton of Oil Equivalent (MMTOE) to OVL by 2017. It will also provide an opportunity to Indian public sector Oil and Gas companies to acquire new technologies from Rosneft. The acquisition is in line the ONGC’s stated objective of adding high quality international assets to India’s Exploration and Production (E&P) portfolio and thereby augmenting India’s energy security.

Recently, an Indian Consortium comprising of Oil India Limited (OIL), Indian Oil Corporation Limited (IOCL) and Bharat PetroResources Limited (BPRL) acquired 23.9% stake in Vankorneft at a cost of US $ 2020.35 million which will give them 6.56 MMTOE. Earlier in May 2016, ONGC Videsh Ltd (OVL) completed the formalities on acquisition of 15% stake in Vankorneft at a cost of US $ 1.284 billion which gave OVL 4.11 MMTOE.

Nobel for Chemistry Goes to Molecular Machine Developers

This year’s Nobel Prize for Chemistry was awarded by the Royal Swedish Academy of Sciences to developers of molecular machines which will "most likely be used in the development of things such as new materials, sensors and energy storage systems".

The developers who have been recognised for their research are Jean-Pierre Sauvage, Sir J. Fraser Stoddart and Bernard L. Feringa for developing the molecular machine.

The announcement from the Royal Swedish Academy of Sciences said,"The development of computing demonstrates how the miniaturisation of technology can lead to a revolution. The 2016 Nobel laureates in Chemistry have miniaturised machines and taken chemistry to a new dimension."

"They have developed molecules with controllable movements, which can perform a task when energy is added… Molecular machines will most likely be used in the development of things such as new materials, sensors and energy storage systems," it added.

IMF Sees Subdued Growth, Warns of Stagnation, Rise in Protectionism

With global growth subpar at 3.1% in 2016, with slight increase to 3.4% next year, persistent stagnation in advanced economies could further fuel anti-trade sentiment with calls for protectionism in developed economies, said IMF in its latest outllok that may send warning bells to India and China.

Global economic growth will remain subdued this year following a slowdown in the United States and Britain’s vote to leave the European Union, the IMF said in its October 2016 World Economic Outlook.

Growth in emerging Asia, and especially India, continues to be resilient, it said. India’s gross domestic product is projected to expand 7.6% this year and next, the fastest pace among the world’s major economies. The IMF urged India to continue reform of its tax system and eliminate subsidies to provide more resources for investments in infrastructure, education, and health care.

On global economy, IMF chief economist Maurice Obstfeld said: “We have slightly marked down 2016 growth prospects for advanced economies while marking up those in the rest of the world."

The 2016 report highlighted the precarious nature of the recovery in 8 years after the global financial crisis. It raised the specter that persistent stagnation, particularly in advanced economies, could further fuel populist calls for restrictions on trade and immigration. Obstfeld said such restrictions would hamper productivity, growth, and innovation.

"It is vitally important to defend the prospects for increasing trade integration," Obstfeld, said. “Turning back the clock on trade can only deepen and prolong the world economy’s current doldrums.”

To support growth in the near term, the central banks in advanced economies should maintain easy monetary policies, spend more on education, technology, and infrastructure, counteract waning potential growth through structural reforms and reduce barriers to market entry, IMF said.

The world economy will expand 3.1% this year, the IMF said, unchanged from its July projection. Next year, growth will increase slightly to 3.4% on the back of recoveries in major emerging market nations, including Russia and Brazil.

Advanced economies will expand just 1.6 %in 2016, less than last year’s 2.1 %pace and down from the July forecast of 1.8 percent.

The IMF marked down its forecast for the United States this year to 1.6 percent, from 2.2% in July, following a disappointing first half caused by weak business investment and diminishing pace of stockpiles of goods. U.S. growth is likely to pick up to 2.2% next year as the drag from lower energy prices and dollar strength fades.

Further increases in the Federal Reserve’s policy rate “should be gradual and tied to clear signs that wages and prices are firming durably,” the IMF said.

Uncertainty following the “Brexit’’ referendum in June will take a toll on the confidence of investors. U.K. growth is predicted to slow to 1.8 % this year and to 1.1%in 2017, down from 2.2% last year.

The euro area will expand 1.7%this year and 1.5% next year, compared with 2% growth in 2015.

“The European Central Bank should maintain its current appropriately accommodative stance,” the IMF said. “Additional easing through expanded asset purchases may be needed if inflation fails to pick up.”

Growth in Japan, the world’s number 3 economy, is expected to remain subdued at 0.5% this year and 0.6% in 2017. In the near term, government spending and easy monetary policy will support growth; in the medium term, Japan’s economy will be hampered by a shrinking population.

In emerging market and developing economies, growth will accelerate for the first time in six years, to 4.2 percent, slightly higher than the July forecast of 4.1 percent. Next year, emerging economies are expected to grow 4.6 percent.

In China, policymakers will continue to shift the economy away from its reliance on investment and industry toward consumption and services, a policy that is expected to slow growth in the short term while building the foundations for a more sustainable long-term expansion. Still, China’s government should take steps to rein in credit that is “increasing at a dangerous pace’’ and cut off support to unviable state-owned enterprises, “accepting the associated slower GDP growth,” the IMF said.

China’s economy, the world’s second largest, is forecast to expand 6.6 %this year and 6.2% in 2017, down from growth of 6.9 % last year.

“External financial conditions and the outlook for emerging market and developing economies will continue to be shaped to a significant extent by market perceptions of China’s prospects for successfully restructuring and rebalancing its economy,’’ the IMF said.

Sub-Saharan Africa’s largest economies continue to struggle with lower commodity revenues, weighing on growth in the region. Nigeria’s economy is forecast to shrink 1.7 %in 2016, and South Africa’s will barely expand. By contrast, several of the region’s non-commodity exporters, including Côte d’Ivoire, Ethiopia, Kenya, and Senegal, are expected to continue to grow at a robust pace of more than 5 %this year.

Economic activity slowed in Latin America, as several countries are mired in recession, with recovery expected to take hold in 2017. Venezuela’s output is forecast to plunge 10 %this year and shrink another 4.5 %in 2017. Brazil will see a contraction of 3.3 %this year, but is expected to grow at 0.5 %in 2017, on the assumption of declining political and policy uncertainty and the waning effects of past economic shocks.

Countries in the Middle East are still confronting challenging conditions from subdued oil prices, as well as civil conflict and terrorism.

Nobel Prize Physics Goes to 3 US Scientists

The Nobel Prize in physics for 2016 has been awarded by the Royal Swedish Academy of Sciences on Tuesday with one half to David J. Thouless of University of Washington, Seattle, US and the other half to F. Duncan M. Haldane of Princeton University, US and J. Michael Kosterlitz of Brown University, Providence, US for theoretical discoveries of topological phase transitions and topological phases of matter.

F. Duncan M. Haldane. Photo: Princeton University, Comms. Office, D. Applewhite

It said, “This year’s Laureates opened the door on an unknown world where matter can assume strange states. They have used advanced mathematical methods to study unusual phases, or states, of matter, such as superconductors, superfluids or thin magnetic films.”

After their pioneering work, the hunt is now on for new and exotic phases of matter and many people are hopeful of future applications in both materials science and electronics, it said in a statement.

The three Laureates’ use of topological concepts in physics was decisive for their discoveries. Topology is a branch of mathematics that describes properties that only change step-wise. Using topology as a tool, they were able to astound the experts. In the early 1970s, Michael Kosterlitz and David Thouless overturned the then current theory that superconductivity or suprafluidity could not occur in thin layers. They demonstrated that superconductivity could occur at low temperatures and also explained the mechanism, phase transition, that makes superconductivity disappear at higher temperatures.

In the 1980s, Thouless was able to explain a previous experiment with very thin electrically conducting layers in which conductance was precisely measured as integer steps. He showed that these integers were topological in their nature. At around the same time, Duncan Haldane discovered how topological concepts can be used to understand the properties of chains of small magnets found in some materials.

We now know of many topological phases, not only in thin layers and threads, but also in ordinary three-dimensional materials. Over the last decade, this area has boosted frontline research in condensed matter physics, not least because of the hope that topological materials could be used in new generations of electronics and superconductors, or in future quantum computers.