Spacex Founder Elon Musk’s BFR Mega Plan Not Practical in 50 Years

Speaking at the International Astronautical Congress in Adelaide, Australia, SpaceX founder Elon Musk revealed the hysteric side of his vision to transport passengers from New York to Shanghai in 39 minutes and sending humans to Mars in 2022 and not beyond as estimated.

“Most of what people consider to be long-distance trips could be completed in less than half-an-hour,” Musk said. Thundering applause to his vision was all that mattered instantly as global media went crazy to give the news headline status and now that the brouhaha subsided, the other side of the story is emerging.

Cost and benefit analysis has shown that the idea is as crazy as the initial failures that had beset SpaceX in its inaugural years.

Here is the time schedule making rounds for the flight at a maximum speed of 27,000 km/hr (17,000 mph) across the world:

* New York to Shanghai in 39 minutes
* Los Angeles to New York in 25 minutes
* Los Angeles to Honolulu in 25 minutes
* London to Dubai in 29 minutes
* New Delhi to Tokyo in 30 minutes

However, airlines industry has remained reluctant to respond as the aviation history is replete with many mega plans going bust before or after take off. The grounding of Concorde supersonic planes is not out of memory of many air travel experts.

Much before the birth of Elon Musk’s SpaceX, Concorde aircraft flew for 30 years from 1976 to 2003 at a cost of $7000 for New York-London flight in 3.5 hours but crashes and safety concerns had cemented its commercaial viability assigning the aircraft to museums now. What Elon Musk is proposing is to bring down the time ten times down but leaving the big safety concern to what he aptly termed Big F**king Rocket.

Other concerns to such aviation plan have not come forth as analysts are still counting on its viability. What one could surmise at this point is that this hysteric plan is beset with flaws of unforeseen hurdles.

First of all, global cities are not in seas as rockets of SpaceX are designed to land on seas and not on landscape. The travel from cities to launchpad is not in Musk’s BFR plan still.

Secondly, safety concerns are given a go-by as SpaceX history is not without failures and no insurance company would come forward to foot the bill as crashes would frequently block any take offs.

Thirdly, the plan is commercially unviable as $2900 for any Trans-Atlantic flight may make the whole idea a luxury or once-in-lifetime experience for many. It may perhaps end up as a tourist attraction than a regular aviation mode.

Finally, Elon Musk is alone in his vision and not backed by other global billiionaires and not certainly by Branson-likes who would go planned to carry out such mega space projects. For now Musk should focus on Mars travel in 2022 than earth-bound unsafe space travel.

Defence Minister visits Ladakh, J&K

Defence Minister Mrs Nirmala Sitharaman visited the forward locations of Leh, Ladakh and Siachen on Saturday, 30 Sept. to review the security situation in the area.

During her visit she was accompanied by The Chief of the Army Staff, The Army Commander, Northern Command and Corps Commander of the Ladakh Corps. The Defence Minister interacted with the soldiers in the remote areas of Siachen Glacier and conveyed her best wishes on the auspicious occasion of Dussehra.

Mrs Sitharaman also inaugurated a bridge on river Shyok on the road between Durbuk and Daulat Beg Oldi (DBO) which was constructed by the BRO. During her visit to Leh she interacted with the troops of Indian Air Force at Air Force Station Leh. Defence Minister Visits J&K, Reviews Security Situation in Valley

On Friday, Mrs. Sitharaman visited the Chinar Corps in Jammu and Kashmir (J&K) to review the overall security situation prevailing in the Valley. She was accompanied by the Chief of the Army Staff General Bipin Rawat, Northern Army Commander Lt General D Anbu and the Chinar Corps Commander Lt Gen J S Sandhu.

She visited the forward areas and was briefed about the robust counter-infiltration posture along the Line of Control. The Defence Minister was subsequently briefed by the Army Commander in Badami Bagh Cantonment on the prevailing security situation in J&K and was given an overview of the counter-infiltration and counter-terrorist operations undertaken in the recent past.

She appreciated the effectiveness of the intelligence and operational grids and commended the troops for the excellent operational successes, which had contributed significantly towards a secure environment in the State.

The Minister complimented the commanders for the high level of synergy achieved with the J&K Police and Central Armed Police Force. Later in the evening, she called on Governor N N Vohra and also interacted with the Chief Minister Ms Mehbooba Mufti.

ARPAN Version 3.0 for Defence Security Corps Rolled Out

Defence Security Corps personnel now have a software ‘ARPAN’ which shall ease personal documentation and all issues related to their progression as the software has been rolled out for faster access and retrieval of information, especially the pension.

The ARPAN software consisting of seven modules facilitates end to end human resource, financial management of Junior Commissioned Officers and Other Ranks with major functional advantages of timely processing of postings, promotions, release of salary, publication of personal occurrences and processing of pension has been rolled out by DCOAS (IS &T) for the Defence Security Corps.

“The software provides valuable data for decision and policy making for the Defence Security Corps Directorate,” said a statement. After launch of this software, Defence Security Corps troops would be able to access their service profiles, statement of accounts and adjustment of allowances at par with the troops of Indian Army. The software has been developed by Tech Mahindra.

MRP Plus GST Display Allowed till December

The government has allowed the manufacturers or packers or importers of pre-packaged commodities to declare the revised retail sale price (MRP) in addition to the existing retail sale price (MRP) for three more months from October 1 to December 31, 2017. Earlier, it was allowed for three months from 1st July 2017 to 30th September, 2017.

The government said the permission was given on account instances where the retail sale price of a pre-packaged commodity is required to be changed but not undertaken yet. The declaration of the changed retail sale price (MRP) was allowed to be made by way of stamping or putting sticker or online printing, as the case may be.

Use of unexhausted packaging material/wrapper was also been allowed upto 30th September, 2017 after making the necessary corrections. “Considering the requests received to extend the permission for some more time it has been extended to display the revised MRP due to implementation of GST by way of stamping or putting sticker or online printing for a further period of three months, up to 31st December, 2017,” said a statement by the Ministry of Consumer Affairs, Food & Public Distribution.

1 in 3 older adults take something to help them sleep but many don’t talk to their doctors

1 in 12 people over age 65 take prescription sleep medications, which carry health risks for older people, U-M/AARP National Poll on Healthy Aging finds.

Sleep doesn’t come easily for nearly half of older Americans, and more than a third have resorted to some sort of medication to help them doze off at night, according to new results from the National Poll on Healthy Aging.

But most poll respondents said they hadn’t talked to their doctor about their sleep, even though more than a third said their sleep posed a problem. Half believe — incorrectly — that sleep problems just come naturally with age.

The poll was conducted by the University of Michigan Institute for Healthcare Policy and Innovation, and is sponsored by AARP and Michigan Medicine, U-M’s academic medical center.

Those who turn to medications may not realize that prescription, over-the-counter and even “natural” sleep aids carry health risks, especially for older adults, either alone or in combination with other substances. In fact, national guidelines strongly warn against prescription sleep medicine use by people over age 65.

Despite this, the nationally representative poll of people ages 65 to 80 finds that 8 percent of older people take prescription sleep medicine regularly or occasionally. Among those who report sleep troubles three or more nights a week, 23 percent use a prescription sleep aid. Most who use such drugs to help them sleep had been taking them for years. Manufacturers and the U.S. Food and Drug Administration say such drugs are only for short-term use.

Medication: not the only option

“Although sleep problems can happen at any age and for many reasons, they can’t be cured by taking a pill, either prescription, over-the-counter or herbal, no matter what the ads on TV say,” says poll director Preeti Malani, M.D., a U-M physician trained in geriatric medicine. “Some of these medications can create big concerns for older adults, from falls and memory issues to confusion and constipation,” even if they’re sold without a prescription.

“The first step for anyone having trouble sleeping on a regular basis should be to talk to a doctor about it,” she continues. “Our poll shows that nearly two-thirds of those who did so got helpful advice – but a large percentage of those with sleep problems simply weren’t talking about it.”

She notes that non-medication-based sleep habits are the first choice for improving sleep in older people. Sleep and health

In all, 46 percent of those polled had trouble falling asleep one or more nights a week. Fifteen percent of the poll respondents said they had trouble falling asleep three or more nights a week.

Other health conditions can contribute to sleep difficulties. Twenty-three percent of poll respondents who had trouble sleeping said it was because of pain. And 40 percent of those with frequent sleep problems said their overall health was fair or poor. Other reasons for sleep troubles included having to get up to use the bathroom at night, and worry or stress.

Insomnia and other irregular sleep patterns can interfere with daytime functioning, and are associated with memory issues, depression and an increased risk of falls and accidents. Even so, many said they didn’t see sleep issues as a health problem – in fact, this belief was the most common reason that poll respondents said they didn’t talk to their doctor about sleep.

This also highlights the need for doctors to ask their older patients about their sleep habits and what they’re doing to address any issues they may be having

“We know that sleep is a critical factor for overall health as we age, and this new research highlights sleep problems as both a significant health issue for older adults and an underacknowledged one both by patients and their providers,” says Alison Bryant, Ph.D., senior vice president of research for AARP. “We need to help people understand that lack of sleep is not just a natural part of aging.”

More about medication use

In all, 14 percent of the poll respondents said they regularly took a prescription sleep medication, prescription pain medication, OTC sleep aid or herbal supplement to help them sleep. Another 23 percent took one of these options occasionally; most of the occasional users said they chose OTC sleep aids.

The most recent Beers Criteria established by the American Geriatrics Society, which guides the use of medications among older people, gives a strong warning against use of prescription sleep drugs, which are sold under such names as Ambien, Lunesta and Sonata.

Meanwhile, even though OTC sleep aids can be purchased without a doctor’s guidance or prescription, they still carry health risks for older people, Malani notes. Most of them contain diphenhydramine, an antihistamine that can cause side effects such as confusion, urinary retention and constipation.

Among poll respondents with frequent sleep problems who took something occasionally to help them sleep, OTC sleep remedies were the most common choice. But among those with frequent sleep issues who took something on a regular basis to try to sleep, prescription sleep medications were the most common option, with 17 percent reporting use.

Use of melatonin and other herbal remedies may be perceived as safer, but less is known about their potential side effects and they are not subject to the FDA’s approval process for medications, says Malani. But any issue that prompts someone to buy an OTC or herbal remedy on a regular basis is something they should discuss with their doctor, she adds.

The poll results are based on answers from a nationally representative sample of 1,065 people ages 65 to 80, who answered a wide range of questions online. Questions were written, and data interpreted and compiled, by the IHPI team. Laptops and Internet access were provided to poll respondents who did not already have it.

Computer scientists address gap in messaging privacy

Researchers have developed a solution to a longstanding problem in the field of end-to-end encryption, a technique that ensures that only sender and recipient can read a message.

With current end-to-end encryption, if an attacker compromises a recipient’s device, they can then put themselves in a position to intercept, read and alter all future communications without sender or recipient ever knowing.

The new protocol, published in IEEE Transactions on Information Forensics and Security, forces attackers to leave evidence of any such activity and alerts users to take action.

Dr. Jiangshan Yu at the University of Luxembourg, Professor Mark Ryan at the University of Birmingham and Professor Cas Cremers at the University of Oxford, were motivated by the discovery of mass software vulnerabilities, such as the Heartbleed bug, that make the majority of devices vulnerable to compromise.

Dr Yu explained, “There are excellent end-to-end encryption services out there, but by definition they rely on your device itself remaining secure; once a device has been compromised there’s little we can do. That’s the problem we wanted to solve.”

Following Edward Snowden’s revelations about government mass surveillance, end-to-end encryption is now widely available through services such as Facebook’s WhatsApp. The approach uses pairs of cryptographic ‘keys’ for the sender to encrypt and the recipient to decrypt messages; anyone wanting to read your messages has to first hack into your phone to steal your latest keys. The attacker then performs a ‘Man-in-the-middle’ (MITM) attack, for example by taking control of your WIFI router to intercept your messages, and uses the stolen keys to impersonate you.

Current encryption protocols such as Signal used by WhatsApp make the most of the fact that a MITM attacker can only intercept messages sent via the compromised network. For example, as soon as you send a message via 3G rather than the compromised WiFi the attacker will no longer be able to act as an intermediary. They will lose track of the keys and be locked out of the conversation.

The solution, called DECIM (Detecting Endpoint Compromise in Messaging), addresses the question of what to do when the attacker is in a position to intercept all of your messages on a long-term basis. Both your Internet Service Provider and messaging service operator are in such positions – all your messages pass through their servers – so that if they obtained your keys, they would never be locked out of a conversation, and you would never know.

With DECIM, the recipient’s device automatically certifies new key pairs, storing the certificates in a tamper-resistant public ledger.

The team undertook a formal security analysis using a symbolic protocol verification tool, the ‘Tamarin prover’, which runs millions of possible attack situations, verifying DECIM’s capabilities. This is a rare step for a messaging protocol, and the same analysis for other protocols revealed several security flaws.

“There’s no silver bullet in the field of end-to-end encryption”, said Dr. Yu, “but we hope that our contribution can add an extra layer of security and help to level the playing field between users and attackers.”

Professor Mark Ryan, from the School of Computer Science at the University of Birmingham, said, “Our Security and Privacy group tries to solve problems that are important to society. Given the prevalence of cyber-attacks on phones and laptops, we are proud of this work on detecting when encryption keys have become compromised. Next, we intend to apply for this work on detecting encryption key compromise to applications, for example in blockchain or in Internet-based voting.”

CARA launches monthly “Jan Sampark” Program to facilitate adoption

The Central Adoption Resource Authority (CARA) of the Ministry of Women & Child Development has started a monthly “Jan Sampark” program to enable the public to have interaction with its officials and staff for seeking information related to Adoption as well as flagging their concerns.

The first of its kind programme was held in New Delhi yesterday. Nearly 150 Prospective Adoptive Parents (PAPs), Adoptive Parents and representatives of agencies participated in the session, which lasted for more than four hours.

Details pertaining to Immediate Placement and Special Needs Adoption Module of Child Adoption Resource Information & Guidance System (CARINGS) as well as the newly launched Grievance/Query portal were shared with all the stakeholders. Also many of the PAPs were counselled and motivated to go for adopting older children.

The event will now be a regular feature every month apart from the quarterly Facebook live chat by CEO CARA.

Government enhances superannuation age of doctors to 65 years

A visionary and pragmatic decision that will strengthen the health services in the country: J P Nadda

The Union Cabinet chaired by the Prime Minister Shri Narendra Modi has approved the enhancement of superannuation age of doctors other than doctors of the Central Health Services (CHS) falling under various Departments/Ministries/autonomous organisations, to 65 years. Union Minister of Health and Family Welfare, Shri J P Nadda, welcomed the Cabinet decision and stated that it is a very visionary and pragmatic decision that will strengthen the health services in the country. “Through this forward looking step, the services of experienced doctors shall be available to bring quality health services to the people. It will help in retaining the existing strength of experienced doctors thereby providing better patient care satisfaction,” Shri Nadda added.

Terming the decision to be people-centered and pro-patient, Shri Nadda further stated that it will address the shortage of doctors. “This is a strong signal that the Government is taking all steps to enhance services/service delivery. This would also help in improving doctor-patient ratio in the country,” Shri Nadda said.

Speaking further on the cabinet decision, Shri Nadda said that the decision will help in proper academic activities in Medical Colleges as also in effective implementation of national health programmes for delivery of health care services. “The decision may not have much financial implications as large numbers of posts are lying vacant and the present incumbents would continue to work in their existing capacity against sanctioned posts. Around 1445 doctors of various Ministries/Departments of the Central Government would be benefitted,” Shri Nadda informed.

According to the Cabinet decision, the superannuation age of doctors under the administrative control of the respective Ministries/Departments [M/o AYUSH (AYUSH Doctors), Department of Defence (civilian doctors under Directorate General of Armed Forces Medical Service), Department of Defence Production (Indian Ordnance Factories Health Service Medical Officers), Dental Doctors under D/o Health & Family Welfare, Dental doctors under Ministry of Railways and of doctors working in Higher Education and Technical Institutions under Department of Higher Education) has been enhanced to 65 years.

The Union Cabinet has approved ex-post facto, the enhancement of superannuation age of doctors working in Central Universities and IITs (Autonomous Bodies) under Department of Higher Education to 65 years; and approved enhancement of superannuation age of doctors in Major Port Trusts (Autonomous Bodies) under Ministry of Shipping to 65 years.

The Union Cabinet has approved that doctors shall hold the administrative posts till the date of attaining the age of 62 years and thereafter their services shall be placed in non-administrative positions.

 

Rescue of US citizen from Leh by IAF Helicopter

On 26 Sep 17, the IAF was requested by US Embassy through Ministry of Defence to help in locating and rescue of US citizen Ms Margaret Allen Stone. Ms Stone had set out for trekking in the Ladakh region and had been held up in Zhingchan area at a distance of 75 Km from Leh since 06 Sep 17 due to injury. Her condition had deteriorated during this prolonged period of lack of care. She was in a critical condition. The US Government informed IAF of the situation in the afternoon hours on 26 Sep 17.

IAF responded to the situation with requisite alacrity. Exact location of Ms Stone was ascertained with the help of civil administration and by evening two IAF helicopters were able to locate Ms Stone in the valley. Ms Stone was brought to the safety of Leh hospital for medical care by sunset on 26 Sep 17.

President of India presents the National Tourism Awards

The President of India, Shri Ram Nath Kovind, presented the National Tourism Awards today (September 27, 2017) at a function held in New Delhi.

Speaking on the occasion, the President said that tourism is one of the largest industries in the world. Its evolution can be estimated from the fact that the number of tourists all over the world has increased from 2.5 crore in 1950 to 123 crore in 2016. The tourism industry contributes 10.2 percent of the world’s GDP. It is estimated that every 10th person in the world works in the tourism industry.

The President said that in India too the livelihood of a very large number of people is linked to the tourism industry. In the year 2016, tourism’s contribution to GDP was 9.6 percent and 9.3 percent to total employment. The tourism industry can contribute significantly in generating permanent employment opportunities and eliminating poverty. According to an assessment, an investment of Rs. 10 lakh in tourism industry provides employment to about 90 people, while about 45 in agriculture, and about 13 people in manufacturing.

The President said that inclusive tourism development can strengthen inclusive economic development. Every citizen should strive to provide a good experience to tourists at his or her own level. In a tourism conscious society, the role of the government is only to provide direction and a facilitating environment.

The President said that ‘Adopt a Heritage Project’ which was launched today, with the efforts of the Tourism Ministry, Culture Ministry and Archaeological Survey of India, has great potential to make our rich and diverse heritage monuments, tourist-friendly. He expressed hope that this project will help in the maintenance of our heritage with a partnership of the public and private sectors.

President’s Durga Puja Greetings

The President of India, Shri Ram Nath Kovind in his message on the eve of Durga Puja has said:-

“On the auspicious occasion of Durga Puja, I extend greetings to my fellow citizens and wish them happiness and prosperity. The festival celebrates the triumph of virtue and destruction of evil.

Durga Puja is also a festival that cherishes the love we feel for daughters in our families. It symbolises feminine energy, empowerment and determination. Let it further our resolve to build a society in which every woman is able to achieve her true potential- and be an equal stakeholder in every avenue of human achievement. May this be a moment of blessing for our country and our collective well-being”.

Group project? Taking turns, working with friends may improve grades

It has become an almost essential element of academic life, from college lecture halls to elementary classrooms: the group assignment.

Dreaded by some, loved by others, group projects typically aim to build teamwork and accountability while students learn about a topic. But depending on the assignment and the structure of the groups, a project can turn out to be a source of great frustration — for instructor and students alike — or the highlight of the school year.

Now a University of Washington-led study of college students has found that the social dynamics of a group, such as whether one person dominates the conversation or whether students work with a friend, affect academic performance. Put simply, the more comfortable students are, the better they do, which yields benefits beyond the classroom.

“They learn more,” explained Elli Theobald, a postdoctoral researcher in the Department of Biology and the lead author on the study, published July 20 in PLOS ONE. “Employers are rating group work as the most important attribute in new recruits and new hires. If students are able to demonstrate that they have worked successfully in groups, it would seem that they should be more likely to land the job.”

Theobald is part of the UW’s Biology Education Research Group lab, formed by several faculty members in the Department of Biology about a decade ago to research how to most effectively teach biology to undergraduates.

A separate study by the BERG lab on group work, published in the July issue of Active Learning in Higher Education, finds that college students, when given a choice of whom to sit and work with in a large classroom setting, gravitate toward those who appear most like them — whether by gender, race and ethnicity, or academic skills.

Over the years, research spanning K-12 through post-secondary education has pointed to the value of group work in fostering collaborative skills and in cementing learning through interaction. In the sciences, labs are a common, though not the only, form of group work, Theobald said. As with many disciplines, STEM fields lend themselves to readings, worksheets and other activities that can be completed by multiple people working together.

For this study, researchers compared survey responses and test scores stemming from two different project styles — single-group and “jigsaw” — with three assignments each during two sections of an introductory biology class at the UW. Each of the 770 students enrolled in one of the two sections of the course experienced each project style at least once. In a single-group activity, student groups completed a worksheet together, relying on their notes and textbooks. In a jigsaw, student groups were assigned specific sections of the worksheet; students then were shuffled to new groups in which each person in the group had completed a different section of the worksheet and could teach their new groupmates what they had learned. Students took an eight-question test after each assignment.

The study found that students who reported a “dominator” in the group fared worse on the tests than those who didn’t express that concern. It also found that students who said they were comfortable in their group performed better than those who said they were less comfortable.

The jigsaw activity appeared to result in more collaboration: Students were 67 percent less likely to report a dominator in jigsaws than in single-group activities. “This suggests that jigsaw activities with intentional structure more effectively promote equity than group activities with less intentional structure,” researchers wrote.

The nearly 770 students who completed all the assignments, tests and surveys had formed two- and three-person groups with those who sat near them in class. (Jigsaw assignments later shuffled initial groups.) Two-thirds of participants were female; people of color, including students who identify as Asian, Under-Represented Minority, and International, made up more than half of respondents.

While the gender and racial and ethnic makeup of the participants informed the study, Theobald said, researchers don’t have details on who worked with whom so as to extrapolate from the composition of groups. For instance, were the experiences of women who worked with men different from those of women who worked in all-female groups? If a group contained only one person of color, what was that person’s experience compared to the rest of the group? That kind of information is ripe for further research, Theobald said.

However, one noticeable data point emerged: International and Asian American students were six times as likely to report a dominator than white American students. “Not all students experience group work the same way,” researchers wrote in the study. “If one student dominates a conversation, it can be particularly jarring to students from cultural backgrounds that place more emphasis on introspection and thinking on one’s own as opposed to a direct relationship between talking as a way to work through ideas.”

Though the data was collected from college students, the findings translate to other settings, Theobald said. She pointed to a study Google conducted to determine what made groups successful — establishing group routines and expectations (“norms”) and adding a brief window at the beginning of work time for casual talk. Such findings, along with those of the UW study, can inform employers as well as K-12 teachers about productive group work, she said.

The younger the students, the more structure a teacher is likely to have to establish, Theobald added. But when teachers make an assignment sufficiently interesting and complex, and manage student behavior, there is a potential for students to work together happily and productively.

“If we can get our groups to be more comfortable, students should learn better and work better,” Theobald said.

New type of supercomputer could be based on ‘magic dust’ combination of light and matter

A team of researchers from the UK and Russia have successfully demonstrated that a type of ‘magic dust’ which combines light and matter can be used to solve complex problems and could eventually surpass the capabilities of even the most powerful supercomputers.

The researchers, from Cambridge, Southampton and Cardiff Universities in the UK and the Skolkovo Institute of Science and Technology in Russia, have used quantum particles known as polaritons – which are half light and half matter – to act as a type of ‘beacon’ showing the way to the simplest solution to complex problems. This entirely new design could form the basis of a new type of computer that can solve problems that are currently unsolvable, in diverse fields such as biology, finance or space travel. The results are reported in the journal Nature Materials.

Our technological progress — from modelling protein folding and behaviour of financial markets to devising new materials and sending fully automated missions into deep space — depends on our ability to find the optimal solution of a mathematical formulation of a problem: the absolute minimum number of steps that it takes to solve that problem.

The search for an optimal solution is analogous to looking for the lowest point in a mountainous terrain with many valleys, trenches, and drops. A hiker may go downhill and think that they have reached the lowest point of the entire landscape, but there may be a deeper drop just behind the next mountain. Such a search may seem daunting in natural terrain, but imagine its complexity in high-dimensional space. “This is exactly the problem to tackle when the objective function to minimise represents a real-life problem with many unknowns, parameters, and constraints,” said Professor Natalia Berloff of Cambridge’s Department of Applied Mathematics and Theoretical Physics and the Skolkovo Institute of Science and Technology, and the paper’s first author.

Modern supercomputers can only deal with a small subset of such problems when the dimension of the function to be minimised is small or when the underlying structure of the problem allows it to find the optimal solution quickly even for a function of large dimensionality. Even a hypothetical quantum computer, if realised, offers at best the quadratic speed-up for the “brute-force” search for the global minimum.

Berloff and her colleagues approached the problem from an unexpected angle: What if instead of moving along the mountainous terrain in search of the lowest point, one fills the landscape with a magical dust that only shines at the deepest level, becoming an easily detectible marker of the solution?

“A few years ago our purely theoretical proposal on how to do this was rejected by three scientific journals,” said Berloff. “One referee said, ‘Who would be crazy enough to try to implement this?!’ So we had to do it ourselves, and now we’ve proved our proposal with experimental data.”

Their ‘magic dust’ polaritons are created by shining a laser at stacked layers of selected atoms such as gallium, arsenic, indium, and aluminium. The electrons in these layers absorb and emit light of a specific colour. Polaritons are ten thousand times lighter than electrons and may achieve sufficient densities to form a new state of matter known as a Bose-Einstein condensate, where the quantum phases of polaritons synchronise and create a single macroscopic quantum object that can be detected through photoluminescence measurements.

The next question the researchers had to address was how to create a potential landscape that corresponds to the function to be minimised and to force polaritons to condense at its lowest point. To do this, the group focused on a particular type of optimisation problem, but a type that is general enough so that any other hard problem can be related to it, namely minimisation of the XY model which is one of the most fundamental models of statistical mechanics. The authors have shown that they can create polaritons at vertices of an arbitrary graph: as polaritons condense, the quantum phases of polaritons arrange themselves in a configuration that correspond to the absolute minimum of the objective function.

“We are just at the beginning of exploring the potential of polariton graphs for solving complex problems,” said co-author Professor Pavlos Lagoudakis, Head of the Hybrid Photonics Lab at the University of Southampton and the Skolkovo Institute of Science and Technology, where the experiments were performed. “We are currently scaling up our device to hundreds of nodes, while testing its fundamental computational power. The ultimate goal is a microchip quantum simulator operating at ambient conditions.”

 

Antibody protects against Zika and dengue, mouse study shows

Brazil and other areas hardest hit by the Zika virus – which can cause babies to be born with abnormally small heads – are also home to dengue virus, which is spread by the same mosquito species.

A new study led by researchers at Washington University School of Medicine in St. Louis shows that an antibody that protects against dengue virus is also effective against Zika in mice.

Antibodies remain in the bloodstream for weeks, so one or a few doses of an antibody-based drug given over the course of a woman’s pregnancy potentially could protect her fetus from Zika, with the added benefit of protecting her from both Zika and dengue disease, the researchers said. Dengue causes high fever, severe headaches, and joint and muscle pain in children and adults but does not directly harm fetuses.

“We found that this antibody not only neutralizes the dengue virus but, in mice, protects both adults and fetuses from Zika disease,” said Michael S. Diamond, MD, PhD, the Herbert S. Gasser Professor of Medicine and the study’s senior author.

The study is published Sept. 25 in Nature Immunology.

Since dengue and Zika are related viruses, the researchers reasoned that an antibody that prevents dengue disease may do the same for Zika. Diamond and graduate student Estefania Fernandez collaborated with Gavin Screaton, MD, DPhil, of Imperial College London, who had generated a panel of human anti-dengue antibodies years before.

The scientists infected nonpregnant adult mice with Zika virus and then administered one of the anti-dengue antibodies one, three or five days after infection. For comparison, another group of mice was infected with Zika virus and then given a placebo. Within three weeks of infection, more than 80 percent of the untreated mice had died, whereas all of the mice that received the anti-dengue antibody within three days of infection were still alive, and 40 percent of those that received the antibody five days after infection survived.

To find out whether the antibody also could protect fetuses from infection, the researchers infected female mice on the sixth day of their pregnancies with Zika virus and then administered a dose of antibody or a placebo one or three days later.

On the 13th day of gestation, the amount of Zika’s genetic material was 600,000 times lower in the placentas and 4,900 times lower in the fetal heads from the pregnant mice that were treated one day after infection, compared with mice that received the placebo. However, administering the antibody three days after infection was less effective: It reduced the amount of viral genetic material in the fetal heads nineteenfold and in the placentas twenty-threefold.

These findings suggest that for the antibody to effectively protect fetuses from Zika infection, it must be administered soon after infection. Such a goal may be unrealistic clinically because women rarely know when they get infected.

However, giving women the antibody as soon as they know they are pregnant could provide them with a ready-made defense against the virus should they encounter it. Antibody-based drugs have been used for decades to provide temporary protection against infectious diseases such as rabies when there is no time to vaccinate or, as in the case of Zika, when there is no vaccine available.

The key to using this antibody as a preventive drug would be to make sure that antibody levels in a woman’s bloodstream stay high enough to protect her fetus for the duration of her pregnancy.

Diamond and colleagues are working on identifying how much antibody a pregnant woman would need to ensure that her fetus is protected from Zika. They also are exploring ways to extend the antibody’s half-life in the blood, to reduce the number of times it would need to be administered.

Having anti-dengue antibodies circulating in the bloodstream for months on end poses a risk, though, because antibodies that protect against one strain of dengue virus sometimes worsen symptoms if a person is infected by another dengue strain.

To avoid the possibility of accidentally aggravating an already very painful disease, the researchers mutated the antibody in four spots, making it impossible for the antibody to exacerbate dengue disease.

“We mutated the antibody so that it could not cause antibody enhancement of dengue infection, and it was still protective,” said Diamond, who is also a professor of pathology and immunology, and of molecular microbiology. “So now we have a version of the antibody that would be therapeutic against both viruses and safe for use in a dengue-endemic area, because it is unable to worsen disease.”

Child abuse affects brain wiring

Impaired neural connections may explain profound and long-lasting effects of traumatic experiences during childhood

  • For the first time, researchers have been able to see changes in the neural structures in specific areas of the brains of people who suffered severe abuse as children.
  • Difficulties associated with severe childhood abuse include increased risks of psychiatric disorders such as depression, as well as high levels of impulsivity, aggressivity, anxiety, more frequent substance abuse, and suicide.
    Severe, non-random physical and/or sexual child abuse affects between 5-15 % of all children under the age of 15 in the Western world.
  • Researchers from the McGill Group for Suicide Studies, based at the Douglas Mental Health University Institute and McGill University’s Department of Psychiatry, have just published research in the American Journal of Psychiatry that suggests that the long-lasting effects of traumatic childhood experiences, like severe abuse, may be due to an impaired structure and functioning of cells in the anterior cingulate cortex. This is a part of the brain which plays an important role in the regulation of emotions and mood.
  • The researchers believe that these changes may contribute to the emergence of depressive disorders and suicidal behaviour.

Crucial insulation for nerve fibres builds up during first two decades of life

For the optimal function and organization of the brain, electrical signals used by neurons may need to travel over long distances to communicate with cells in other regions. The longer axons of this kind are generally covered by a fatty coating called myelin. Myelin sheaths protect the axons and help them to conduct electrical signals more efficiently. Myelin builds up progressively (in a process known as myelination) mainly during childhood, and then continue to mature until early adulthood.

Earlier studies had shown significant abnormalities in the white matter in the brains of people who had experienced child abuse. (White matter is mostly made up of billions of myelinated nerve fibres stacked together.) But, because these observations were made by looking at the brains of living people using MRI, it was impossible to gain a clear picture of the white matter cells and molecules that were affected.

To gain a clearer picture of the microscopic changes which occur in the brains of adults who have experienced child abuse, and thanks to the availability of brain samples from the Douglas-Bell Canada Brain Bank (where, as well as the brain matter itself there is a lot of information about the lives of their donors) the researchers were able to compare post-mortem brain samples from three different groups of adults: people who had committed suicide who suffered from depression and had a history of severe childhood abuse (27 individuals); people with depression who had committed suicide but who had no history of being abused as children (25 individuals); and brain tissue from a third group of people who had neither psychiatric illnesses nor a history of child abuse (26 people).

Impaired neural connectivity may affect the regulation of emotions

The researchers discovered that the thickness of the myelin coating of a significant proportion of the nerve fibres was reduced ONLY in the brains of those who had suffered from child abuse. They also found underlying molecular alterations that selectively affect the cells that are responsible for myelin generation and maintenance. Finally, they found increases in the diameters of some of the largest axons among only this group and they speculate that together, these changes may alter functional coupling between the cingulate cortex and subcortical structures such as the amygdala and nucleus accumbens (areas of the brain linked respectively to emotional regulation and to reward and satisfaction) and contribute to altered emotional processing in people who have been abused during childhood.

The researchers conclude that adversity in early life may lastingly disrupt a range of neural functions in the anterior cingulate cortex. And while they don’t yet know where in the brain and when during development, and how, at a molecular level these effects are sufficient to have an impact on the regulation of emotions and attachment, they are now planning to explore this in further research.

Goodbye, login. Hello, heart scan

Forget fingerprint computer identification or retinal scanning. A University at Buffalo-led team has developed a computer security system using the dimensions of your heart as your identifier.

The system uses low-level Doppler radar to measure your heart, and then continually monitors your heart to make sure no one else has stepped in to run your computer.

The technology is described in a paper that the inventors will present at next month’s 23rd Annual International Conference on Mobile Computing and Communication (MobiCom) in Utah. The system is a safe and potentially more effective alternative to passwords and other biometric identifiers, they say. It may eventually be used for smartphones and at airport screening barricades.

“We would like to use it for every computer because everyone needs privacy,” said Wenyao Xu, PhD, the study’s lead author, and an assistant professor in the Department of Computer Science and Engineering in UB’s School of Engineering and Applied Sciences.

“Logging-in and logging-out are tedious,” he said.

The signal strength of the system’s radar “is much less than Wi-Fi,” and therefore does not pose any health threat, Xu said.

“We are living in a Wi-Fi surrounding environment every day, and the new system is as safe as those Wi-Fi devices,” he said. “The reader is about 5 milliwatts, even less than 1 percent of the radiation from our smartphones.”

The system needs about 8 seconds to scan a heart the first time, and thereafter the monitor can continuously recognize that heart.

The system, which was three years in the making, uses the geometry of the heart, its shape and size, and how it moves to make an identification. “No two people with identical hearts have ever been found,” Xu said. And people’s hearts do not change shape, unless they suffer from serious heart disease, he said.

Heart-based biometrics systems have been used for almost a decade, primarily with electrodes measuring electrocardiogram signals, “but no one has done a non-contact remote device to characterize our hearts’ geometry traits for identification,” he said.

The new system has several advantages over current biometric tools, like fingerprints and retinal scans, Xu said. First, it is a passive, non-contact device, so users are not bothered with authenticating themselves whenever they log-in. And second, it monitors users constantly. This means the computer will not operate if a different person is in front of it. Therefore, people do not have to remember to log-off when away from their computers.

Xu plans to miniaturize the system and have it installed onto the corners of computer keyboards. The system could also be used for user identification on cell phones. For airport identification, a device could monitor a person up to 30 meters away.

Xu and collaborators will present the paper — “Cardiac Scan: A Non-contact and Continuous Heart-based User Authentication System” — at MobiCom, which is billed as the flagship conference in mobile computing. Organized by the Association for Computing Machinery, the conferernce will be held from Oct. 16-20 in Snowbird, Utah.

Additional authors are, from the UB Department of Computer Science and Engineering, Feng Lin, PhD (now an assistant professor at the University of Colorado Denver); Chen Song, a PhD student; Yan Zhuang, a master’s student; and Kui Ren, PhD, SUNY Empire Innovation Professor; and from Texas Tech University, Changzhi Li, PhD.

Weight loss for adults at any age leads to cost savings, study suggests

Helping an adult lose weight leads to significant cost savings at any age, with those savings peaking at age 50, suggests a new Johns Hopkins Bloomberg School of Public Health study.

The findings, which will be published online September 26 in the journal Obesity, suggests that a 20-year-old adult who goes from being obese to overweight would save an average of $17,655 in direct medical costs and productivity losses over their lifetime. If the same person were to go from being obese to a healthy weight, an average savings of $28,020 in direct medical costs and productivity losses can occur. Helping a 40-year-old adult go from being obese to overweight can save an average of $18,262. If the same person went from being obese to normal weight, an average savings of $31,447 can follow.

A high body mass index (BMI) is linked to a higher risk of serious conditions like diabetes, cardiovascular disease and some cancers. Subsequently, a high BMI and associated conditions can lead to high medical and societal costs and productivity losses. More than 70 percent of adults in the U.S. are considered to be overweight or obese, which in direct medical expenses alone costs nearly $210 billion per year.

“Over half the costs of being overweight can be from productivity losses, mainly due to missed work days but also productivity losses. This means that just focusing on medical costs misses a big part of the picture, though they’re a consideration, too,” says Bruce Y. Lee, MD, MBA, executive director of the Global Obesity Prevention Center (GOPC) at the Bloomberg School. “Productivity losses affect businesses, which in turn affects the economy, which then affects everyone.”

When absenteeism occurs in the workforce, others, at times, have to take on a larger workload. This all funnels downstream and adds to the societal costs of obesity. And health insurance premiums increase across the board, even for healthy patients, as insurers spread the cost of obesity and its associated conditions.

For the study, the researchers developed a computational simulation model to represent the U.S. adult population to show the lifetime costs and health effects for an individual with obesity, overweight and healthy weight statuses at ages 20 through 80 in increments of 10. The model used data from the Coronary Artery Disease Risk Development in Young Adults (CARDIA) and Atherosclerosis Risk in Communities (ARIC) studies and included 15 mutually exclusive health statuses that represented every combination of three BMI categories (normal weight, overweight and obesity) and five chronic health stages.

The model simulated the weight and health status of an adult as he or she ages year by year throughout his or her lifetime to track the individual medical costs and productivity losses of each person. The estimated direct medical costs to the insurer and health care facility, productivity losses and sick time were included.

The research team found that cost savings peak at age 50 with an average total savings of $36,278. After age 50, the largest cost savings occur when an individual with obesity moves to the normal weight category as opposed to the overweight category, emphasizing the importance of weight loss as people age. This finding is important because people aged 50 and older make up more than 60% incremental societal costs, which includes higher taxes to support government insurance and higher copays and other out-of-pocket expenses.

“Most previous models have taken into account one or a few health risks associated with obesity. Subsequently, the forecasted costs may be unrealistic,” says Saeideh Fallah-Fini, PhD, a former GOPC visiting scholar who was part of the research team. “In our study, the model we developed takes into account a range of immediate health complications associated with body weight, like hypertension or diabetes, as well as all major long-term adverse health outcomes, including heart disease and some types of cancer, in forecasting the incremental health effects and costs to give a realistic calculation.”

Results from this study could inform policymakers about the specific implications and costs associated with obesity in order to design more successful interventions that are tailored to specific groups (defined by age, current health condition and weight). Understanding the resulting lifetime costs and health effects for an individual with obesity at different ages can also aid physicians and other health care professionals in implementing more targeted preventive management decisions for patients with high BMIs and associated health conditions. On the flip side, it could be beneficial for patients to better understand the health outcomes associated with potential future health risks and impending medical costs, given their existing BMI status and health condition.

Finally, realizing the reverberating effects of obesity on the productivity of their employees and consequently their profits, employers may look to redesign or sponsor healthy lifestyle programs with weight-loss initiatives. In turn, this could decrease absenteeism and poor performance. “In the end, the heart of a business is its employees,” says Lee. “Having employees who are overweight and unhealthy is akin to a football team trying to compete with chronically injured players.”

Kandla Port renamed as Deendayal Port

The Ministry of Shipping has issued a notification renaming Kandla Port Trust as Deendayal Port Trust with effect from 25th of September, 2017. Kandla Port, located on the Gulf of Kutch in Gujarat, is one of the twelve major ports in the country. As per the Ministry’s notification, the Central Government, in exercise of powers conferred on it under Indian Ports Act, 1908, made the amendment to replace “Kandla” with “Deendayal”.

While inaugurating various projects at Kandla Port in May this year, Prime Minister Shri Narendra Modi had given the suggestion for renaming of Kandla Port after Pandit Deendayal Upadhyay, who stood for the uplift of the poor and weaker sections of society. The Ministry of Shipping issued the required notification on the occasion of the closing of the year long centenary celebrations of Pandit Deendayal Upadhyay.

Vice-President inaugurates a “Crusade for Toilets” in Karnataka

The Vice President, Shri M Venkaiah Naidu, today inaugurated the “Swachhta Hi Seva” and “Shouchalayakkagi Samara” (A Crusade For Toilets) Programme in Karnataka. He was presiding as the Chief Guest over a public event at Hubli.

The Vice President later visited Konnur Village, in Naragund Taluk, Gadag District, where he initiatied the activity of ‘Tippe Samskarane’ (Waste Processing). He also inaugurated a “Shudda Kudiyuva Neerina Ghataka” (Purified Drinking Water Plant), visited the Janata Colony in the village, and addressed a “Shouchalayakkagi Samara” public gathering at the local high school.

Speaking on the occasion, the Vice President emphasized the need for Swachhata to become a jan aandolan. He complimented the taluka, district and State for the good progress made by them. He urged all present to participate in Swachhata activities and said that Swachh Bharat Mission is a national program, a people’s program, and not one of any particular political party. He gave several examples of ordinary people making extraordinary contributions, including Ms Lavanya, a young girl from Karnataka who persuaded her unwilling family to build a toilet and then went on to inspire her entire village. The Vice President appreciated the fact that many young women are now demanding toilets before they get married into another family.

On the occasion, the Vice President also honoured 13 Village Panchayat Presidents and the Naragund Taluka Panchayat President, the achievers of “Shouchalayakkagi Samara”. He also declared the rural areas of Naragund Taluk as an ODF block.

Shri Vajubhai Rudabhai Vala, the Governor of Karnataka, began his address by thanking the Vice President for starting the Swachhata Hi Seva campaign from Karnataka. He also emphasized the importance of caring for one another, as enshrined in the slogan of the government, ‘Sabka Saath, Sabka Vikas’. He said that to care for others, we need to start by taking the initiative ourselves in the direction of a Swachh Bharat.

Shri Ramesh Jigajinagi, the Minister of State, Drinking Water and Sanitation, congratulated the State government on the occasion and re-emphasized the importance of the Swachhata Hi Seva campaign. He reiterated the fact that the Prime Minister, Shri Narendra Modi, in his recent visit to Uttar Pradesh, had appreciated the naming of a toilet as “Izzat Ghar”.

Shri H.K. Patil, Karnataka Minister for Rural development and Panchayati Raj, gave a snapshot of the progress being made by the State under the Swachh Bharat Mission and said that both, the State and the nation, were moving at a good pace towards becoming clean and free from open defecation.

In his welcome address at the gathering, Shri Parameswaran Iyer, the Secretary, Ministry of Drinking Water and Sanitation, shared a nationwide progress update on Swachh Bharat Mission and appreciated the good progress being made by the Government of Karnataka in meeting the goals of the Mission.

Shri P.C. Gaddigoudar, Member of Parliament, Lok Sabha, and Shri B.R. Yavagal, MLA, Naragund, were also present on the occasion.

Sachin Tendulkar Participates in the Swacchata Hi Seva Campaign

Cricket legend Sachin Tendulkar came out in support of Prime Minister Narendra Modi’s Swachhta Hi Seva campaign leading the cleanliness campaign in Mumbai. He did ‘shramdaan’ by cleaning the streets in Bandra. Continuing the trend of celebrity support to this campaign Malayalam superstar Mammootty has accepted Prime Minister Narendra Modi invitation to participate in the Swachhta Hi Seva movement.

The campaign also saw endorsement from faith leaders. In a special event, hundreds of volunteers came together to participate in a swachhata drive from Laxman Jhula to Ram Jhula in Rishikesh. Organised by members of Parmarth Niketan, Rishikesh’s largest ashram, the event also saw participation of Swachh Bharat Mission officials as well as foreign visitors from more than 10 countries.

National Cadet Corps Officer Training Academy, Kamptee also launched the fortnight long ‘Swachhta Hi Seva’ cleanliness campaign. Maj Gen AP Bam, SM, VSM, Commandant, Officers and Staff of Academy, Course students of Pre-Commission Course and Permanent Instructors of various NCC Units of all three services of Indian Armed Forces attended the programme.

‘Samagra Swachhata” became the philosophy in Meghalaya at an event in Mylliem Block, where the Governor, Shri Banwarilal Purohit graced the occasion. Madhya Pradesh and Uttarakhand have launched several “Swachhta Hi Seva Rath” reaching the unreached areas and spreading the message about the safe toilet technology, health and hygiene amongst community. In J&K, garbage from various areas situated on the banks of Wullar lake was collected and disposed of in true spirit of Swachhta Hi Seva.

Acting as an inspiration for many, in Jamshedpur a Class VII girl built a public toilet from her 2-year savings and was honoured by the Hon’ble Chief Minister as a sanitation champion certificate.