TikTok’s mental health ‘minefield’ may be unreliable or misleading: Study

Social media platforms have become a go-to source for mental health information, especially among young users. But a new study suggests that much of what people encounter online, particularly on TikTok, may be unreliable or even misleading.

Researchers from the University of East Anglia (UEA) found that a significant share of posts related to conditions such as ADHD and autism contain inaccuracies or lack proper evidence. Their analysis, which covered multiple platforms including YouTube, Facebook, Instagram and X, points to a broader issue: misinformation around mental health is widespread, and in some cases, alarmingly high.

The study reviewed more than 5,000 posts across a range of mental health topics, from anxiety and depression to schizophrenia and eating disorders. It found that misleading content could make up as much as 56 per cent of posts in certain areas, highlighting how easily unverified claims can spread in highly engaging formats like short videos.

Among all platforms, TikTok stood out for having the highest levels of questionable content. According to the researchers, over half of the ADHD-related videos analysed, and around 52 per cent were found to be inaccurate. For autism-related content, the figure stood at 41 per cent. By comparison, misinformation rates were lower on YouTube, averaging about 22 per cent, and even lower on Facebook at under 15 per cent.

Experts say this matters because social media is increasingly shaping how young people understand their mental health. Many turn to these platforms to interpret symptoms or self-diagnose conditions. While this can sometimes prompt useful self-reflection, it also carries risks when the information is incomplete or incorrect.

Misleading content can blur the line between normal behaviour and clinical conditions, potentially leading people to wrongly believe they have a disorder, or, conversely, delay seeking help when they actually need it. It may also reinforce stigma, create unnecessary fear, or promote treatments that lack scientific backing.

The study also highlights a stark divide between who is creating content and how reliable it is. Posts made by healthcare professionals were consistently more accurate, but they represent only a small fraction of what users see. For instance, just 3 per cent of ADHD-related videos by professionals contained misinformation, compared to 55 per cent among non-professional creators.

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At the same time, the researchers acknowledge that personal stories and lived experiences shared by individuals can play a valuable role in raising awareness and helping others feel understood. The challenge lies in ensuring that such content is complemented by clear, evidence-based guidance from qualified experts.

Another key factor driving misinformation is the way platforms like TikTok operate. Their algorithms tend to prioritise content that is engaging and widely shared, regardless of its accuracy. Once users show interest in a topic, they are often fed a steady stream of similar videos, creating echo chambers where misleading ideas can quickly gain traction.

There are, however, some exceptions. The study found that YouTube Kids performed notably better, with no misinformation detected in content related to anxiety and depression, and relatively low levels, and around 8.9 per cent for ADHD. Researchers attribute this to stricter moderation and content controls.

Overall, the findings point to a growing need for stronger safeguards. The authors call for better moderation systems, clearer standards for identifying misinformation, and more active participation from clinicians and health organisations in creating accessible, trustworthy content.

As social media continues to shape public understanding of mental health, the study makes one thing clear: while these platforms can be powerful tools for awareness, without reliable information, they can just as easily become a source of confusion.

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Less psychedelic, more medical magic mushrooms

The psychoactive substance of magic mushrooms, psilocybin, is under scientific scrutiny as being useful in the treatment of neuropsychiatric disorders such as depression, anxiety, substance use disorder and some neurodegenerative diseases. It can be limited to broader therapeutic uses, however, by the hallucinogenic effects. A study on the effects of psilocin, the active compound in psilocybin, on mice published in the Journal of Medicinal Chemistry by researchers synthesized modified versions of psilocin which preserve its properties but have fewer hallucinogenic-like effects than pharmaceutical-grade psilocybin.

In line with the emerging scientific view that psychedelic and serotonergic works can be decoupled, one correspondent author of the study, Andrea Mattarei, states that their findings align with this emerging school of thought. This creates the prospect of developing new therapies that are more biologically active but less hallucinogenic, which might allow developing safer and more practicable treatment options.

Mood disorders as well as certain neurodegenerative ailments such as the Alzheimer disease entail an imbalance of the neurotransmitter molecule serotonin that aids in controlling moods and other brain processes. Psychedelics have been studied to have therapeutic effects against serotonin-signaling pathways in decades by scientists. But the hallucinations that can be used along with these drugs can cause people to fear their use even in case there is a medical advantage.

Brain Image (NIH)

Therefore, a group supervised by Sara De Martin, Mattarei and Paolo Manfredi chemically engineered 5 psilocin analogs to release gradually, slowly and possibly non-hallucinogenic into the brain. The initial test of the five compounds was conducted using human plasma samples and the laboratory parameters that replicate gastrointestinal absorption. These tests have enabled the group to determine a compound they refer to as 4e as the best prospect since it exhibited desirable stability to be absorbed and allowed a slow release of psilocin – a trait that has the potential to reduce the effects of hallucinations. Notably, 4e was also active at major serotonin receptors, and at similar levels as psilocin.

The researchers then compared the impact of the same dosage of 4e on mice with pharmaceutical quality psilocybin. The team orally gave the compounds to mice and assessed the degree to which psilocin was absorbed by the bloodstream and the brain after 48 hours. The compound had the capability of penetrating the blood-brain barrier in mice treated with 4e and had a lower yet more prolonged presence of psilocin in their brain than did their psilocybin-treated counterparts. In examining the behavior of the mice, the researchers found that the 4e-treated mice had reduced the number of head twitches, a well-established oral psychiatric effect of psychedelics in rodents, with the 4e-treated mice compared to those treated with psilocybin having far fewer head twitches. This difference in behavior seemed to be linked with the quantity and the time that psilocin was released in the brain.

According to the researchers, the results of their experiments testify to the possibility of creating stable derivatives of psilocin penetrating the brain and preserving the function of serotonin receptors without acute psychotropic effects. Their mechanism of action and complete description of their biological effects will require further research before their therapeutic capacity and safety in human beings are evaluated.

The authors admit MGGM Therapeutics, LLC. funding in partnership with NeuroArbor Therapeutics Inc. Some of the authors state that they are patent holders regarding psilocin.

Aid teams highlight growing anxiety in Gaza after food is looted

“Fifteen World Food Programme trucks were looted late last night in Southern Gaza, while en route to WFP-supported bakeries,” the UN agency said. “These trucks were transporting critical food supplies for hungry populations waiting anxiously for assistance.”

The development is a blow to continuing efforts to help Gaza’s most vulnerable people after Israel allowed a limited number of aid trucks into Gaza earlier this week, following an 11-week total blockade.

Today, Gazans face “hunger, desperation and anxiety over whether more food aid is coming”, WFP said, noting that the uncertainty “is contributing to rising insecurity”.

“We need support from the Israeli authorities to get far greater volumes of food assistance into Gaza faster, more consistently and transported along safer routes, as was done during the ceasefire,” it insisted.

More to come on this developing story…

Did the pandemic change our personalities? Increased neuroticism among young adults seen: Study

Despite a long-standing hypothesis that personality traits are relatively impervious to environmental pressures, the COVID-19 pandemic may have altered the trajectory of personality across the United States, especially in younger adults, according to a new study published this week in the open-access journal PLOS ONE by Angelina Sutin of Florida State University College of Medicine, and colleagues.

Previous studies have generally found no associations between collective stressful events—such as earthquakes and hurricanes—and personality change. However, the coronavirus pandemic has affected the entire globe and nearly every aspect of life.

In the new study, the researchers used longitudinal assessments of personality from 7,109 people enrolled in the online Understanding America Study. They compared five-factor model personality traits—neuroticism, extraversion, openness, agreeableness and conscientiousness—between pre-pandemic measurements (May 2014 – February 2020) and assessments early (March – December 2020) or later (2021-2022) in the pandemic. A total of 18,623 assessments, or a mean of 2.62 per participant, were analyzed. Participants were 41.2% male and ranged in age from 18 to 109.

A crowd of people at a pedestrian crossing./CREDIT:Brian Merrill, Pixabay, CC0(https://creativecommons.org/publicdomain/zero/1.0/)

Consistent with other studies, there were relatively few changes between pre-pandemic and 2020 personality traits, with only a small decline in neuroticism. However, there were declines in extraversion, openness, agreeableness, and conscientiousness when 2021-2022 data was compared to pre-pandemic personality. The changes were about one-tenth of a standard deviation, which is equivalent to about one decade of normative personality change. The changes were moderated by age, with younger adults showing disrupted maturity in the form of increased neuroticism and decreased agreeableness and conscientiousness, and the oldest group of adults showing no statistically significant changes in traits.

The authors conclude that if these changes are enduring, it suggests that population-wide stressful events can slightly bend the trajectory of personality, especially in younger adults.

The authors add: “There was limited personality change early in the pandemic but striking changes starting in 2021. Of most note, the personality of young adults changed the most, with marked increases in neuroticism and declines in agreeableness and conscientiousness. That is, younger adults became moodier and more prone to stress, less cooperative and trusting, and less restrained and responsible.”

Meal timing may influence mood vulnerability; Daytime eating benefits mental health

“Our findings provide evidence for the timing of food intake as a novel strategy to potentially minimize mood vulnerability in individuals experiencing circadian misalignment, such as people engaged in shift work, experiencing jet lag, or suffering from circadian rhythm disorders,” said co-corresponding author Frank A. J. L. Scheer, PhD, Director of the Medical Chronobiology Program in the Brigham’s Division of Sleep and Circadian Disorders. “Future studies in shift workers and clinical populations are required to firmly establish if changes in meal timing can prevent their increased mood vulnerability. Until then, our study brings a new ‘player’ to the table: the timing of food intake matters for our mood.”

Shift workers account for up to 20 percent of the workforce in industrial societies and are directly responsible for many hospital services, factory work, and other essential services. Shift workers often experience a misalignment between their central circadian clock in the brain and daily behaviors, such as sleep/wake and fasting/eating cycles. Importantly, they also have a 25 to 40 percent higher risk of depression and anxiety.

Eating/Photo:en.wikipedia.org

“Shift workers — as well as individuals experiencing circadian disruption, including jet lag — may benefit from our meal timing intervention,” said co-corresponding author Sarah L. Chellappa, MD, PhD, who completed work on this project while at the Brigham.“Our findings open the door for a novel sleep/circadian behavioral strategy that might also benefit individuals experiencing mental health disorders. Our study adds to a growing body of evidence finding that strategies that optimize sleep and circadian rhythms may help promote mental health.”

To conduct the study, Scheer, Chellappa, and colleagues enrolled 19 participants (12 men and 7 women) for a randomized controlled study. Participants underwent a Forced Desynchrony protocol in dim light for four 28-hour “days,” such that by the fourth “day” their behavioral cycles were inverted by 12 hours, simulating night work and causing circadian misalignment. Participants were randomly assigned to one of two meal timing groups: the Daytime and Nighttime Meal Control Group, which had meals according to a 28-hour cycle (resulting in eating both during the night and day, which is typical among night workers), and the Daytime-Only Meal Intervention Group, which had meals on a 24-hour cycle (resulting in eating only during the day). The team assessed depression- and anxiety-like mood levels every hour.

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The team found that meal timing significantly affected the participants’ mood levels. During the simulated night shift (day 4), those in the Daytime and Nighttime Meal Control Group had increased depression-like mood levels and anxiety-like mood levels, compared to baseline (day 1). In contrast, there were no changes in mood in the Daytime Meal Intervention Group during the simulated night shift. Participants with a greater degree of circadian misalignment experienced more depression– and anxiety-like mood.

“Meal timing is emerging as an important aspect of nutrition that may influence physical health,” said Chellappa. “But the causal role of the timing of food intake on mental health remains to be tested. Future studies are required to establish if changes in meal timing can help individuals experiencing depressive and anxiety/anxiety-related disorders.”