More than 50 million in West and Central Africa at risk of hunger

More than 36 million are struggling to meet their basic food needs, which is projected to rise to over 52 million during the lean season from June to August, latest analysis reveals.

This includes almost three million people facing emergency conditions, and 2,600 people in Mali who are at risk of catastrophic hunger.

Although needs are at a historic high, resources are limited, with millions of lives at stake. 

Without immediate funding, WFP will be forced to scale down even further both in the number of people reached and the size of food rations distributed,” said Margot van der Velden, Regional Director for West and Central Africa. 

‘Extremely difficult and dire’ 

In 2019, only four per cent of the population was food insecure compared to 30 per cent today, according to Ollo Sib, a senior research adviser with WFP.

“We hope that our voice will be heard because this food security situation in the Sahel remains extremely difficult and dire,” he said, speaking from Dakar to journalists in Geneva.

Mr. Sib recently travelled to some of the affected areas, such as communities in northern Ghana grappling with unprecedented drought.

“They were forced to replant two to three times, and for them, each failed sowing is an additional financial burden as the cost of fertilisers and seeds were extremely high in those locations,” he said.

The assessment team also went to northern Mali, which is the only place in the region where people are facing catastrophic food security conditions.

“We had the opportunity to interact with pastoralist elders who typically sell their livestock to buy cereals,” he said. 

“This year they were worried because the cost of food rose by 50 per cent compared to the five-year average. But at the same time, they are not able to access markets to sell their goods.” 

Fighting, food inflation and floods

WFP said unyielding conflict is among the factors driving deepening hunger in West and Central Africa.  

Fighting has displaced more than 10 million of the most vulnerable people across the region, including more than two million refugees and asylum seekers, in Chad, Cameroon, Mauritania and Niger. 

Nearly eight million more have been internally displaced, mainly in Nigeria and Cameroon. 

Meanwhile, food inflation exacerbated by rising food and fuel costs are pushing hunger levels to new highs.

At the same time, recurrent extreme weather “erodes the ability of families to feed themselves,” WFP said. 

Vulnerable populations in Morolaba, Burkina Faso, receive emergency airlifted food assistance.

© WFP/Desire Joseph Ouedraogo

Vulnerable populations in Morolaba, Burkina Faso, receive emergency airlifted food assistance.

Five million at risk

WFP stands ready to respond and scale up vital assistance in West Africa and the Sahel. The UN agency is seeking $710 million to support its life-saving operations through the end of October.

The aim is to reach almost 12 million people this year with critical assistance.

So far, teams have already reached three million of the most vulnerable including refugees, internally displaced people, malnourished children under five, and pregnant or breastfeeding women and girls.

The agency said that five million risk losing assistance unless urgent funding is found.

Address root causes

WFP also called for governments and partners to invest in sustainable solutions aimed at building resilience and reducing long-term dependency on aid.

Since 2018, the UN agency has been working with regional governments to address the root causes of hunger through a programme that has rehabilitated over 300,000 hectares of land to support over four million people in more than 3,400 villages. 

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Gazans face hunger crisis as aid blockade nears two months

Both the UN agency that assists Palestine refugees, UNRWA, and the World Food Programme (WFP) report that food stocks are now exhausted, even as supplies of lifesaving assistance pile up at border crossings waiting to be brought in.

Humanitarians continue to warn that hunger is spreading and deepening in the enclave, amid the blockage, access constraints, ongoing Israeli military operations and a rise in looting.

Scarcity, sharing and shame

UNRWA shared the testimony of a woman called Um Muhammad who is staying at a shelter in Gaza City and prepares food for 11 family members daily. Although she still has some flour, most families nearby have already run out.

“When I knead and bake, I feel very ashamed of myself, so I distribute some bread to the children who come asking for a piece of bread,” she said.

“We eat one meal a day, dividing bread among each person daily. We eat canned goods, lentils, and rice. When this stock runs out, I don’t know what we will do because what is available in the market is scarce.”

Longest blockade

Gaza has a population of more than two million people who mostly depend on aid, but no humanitarian or commercial supplies have entered since 2 March when Israel imposed a full blockade on the territory.  

This is by far the longest ban on aid moving into the Strip since the start of the war in October 2023, following the deadly Hamas-led terror attacks on Israel.

The situation has led to shortages – not just of food, but other items including medicine, shelter supplies and safe water.  WFP recently noted a 1,400 per cent increase in food prices when compared to the ceasefire period, which lasted from 19 January to 18 March of this year.

Malnutrition and looting

On Friday, the UN agency delivered its last remaining stocks to hot meals kitchens, which have been a lifeline in recent weeks. The kitchens are expected to fully run out of food within days, and another 16 closed over the weekend.  Furthermore, all 25 WFP-supported bakeries are now shuttered.

There has been an increase in reports of looting incidents, the UN humanitarian affairs office OCHA said on Monday. Over the weekend, armed individuals reportedly ransacked a truck in Deir Al-Balah and a warehouse in Gaza City.

Meanwhile, the latest famine review analysis by the Integrated Food Security Phase Classification (IPC) got underway this week.

Humanitarian partners warn that the nutrition situation across Gaza is worsening. Since January, about 10,000 cases of acute malnutrition among children have been identified, including 1,600 cases of severe acute malnutrition

Although treatment supplies remain available in the south, accessing them continues to be extremely challenging due to operational and security restrictions.

Healthcare also affected

OCHA stressed that the depletion of critical stocks in Gaza goes far beyond food. For example, trauma-related medical supplies are running out at a time when the number of people injured in mass casualty incidents continues to increase. 

Gaza also lacks surgical supplies, including gowns, drapes and gloves.  The World Health Organization (WHO) informed that their warehouse has run out of therapeutic milk, intravenous antibiotics and painkillers, as well as spare parts for ambulances and oxygen stations. 

Partners working in health add that an increasing number of critical staff are being denied access to Gaza, with a rise in the denial of entry for emergency medical teams, particularly highly specialized professionals – including orthopedic and plastic surgeons – and a recent restriction of movement across the enclave.  

Aid awaiting entry

As the aid ban continues, humanitarians are doing everything possible to reach people with whatever supplies remain available.

They also have stocks of food and other lifesaving items ready and waiting to enter the Gaza Strip as soon as border crossings re-open.

This includes nearly 3,000 UNRWA trucks of aid, while WFP has more than 116,000 metric tonnes of food assistance – enough to feed one million people for up to four months. 

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Hunger-controlling brain cells may offer path for new obesity drugs

Is the solution to the obesity epidemic all in our heads? A study by researchers at The Rockefeller University suggests that it might be.

“We have identified two new populations of cells in the brain that potently regulate appetite,” says Alexander Nectow, first author of the paper, published in Cell on July 27. The two types of cells, located in a part of the brainstem called the dorsal raphe nucleus, are potential targets for new drugs to treat obesity by controlling the hunger signals that drive the search for and consumption of food.

The new findings are the latest evidence that eating is a complex biological behavior mediated by multiple sites in the brain. They also offer a possible solution to a problem that has dogged previous efforts to address obesity at the neuronal level.

In 1994, Jeffrey Friedman, Marilyn M. Simpson Professor and head of Rockefeller’s Laboratory of Molecular Genetics, launched a new era in obesity research by discovering a hormone called leptin, which acts on neurons in the brain’s hypothalamus region to suppress hunger. Injections of the hormone have been shown to promote dramatic weight loss in patients with a rare leptin deficiency, however many obese people don’t respond to this therapy.

“Obesity is generally associated with leptin resistance,” says Friedman, whose lab produced the new study. “And our recent data suggest that modulation of the activity of specific neurons with drugs could bypass leptin resistance and provide a new means for reducing body weight.”

The cells that trigger eating

Nectow and his colleagues zeroed in on the dorsal raphe nucleus, or DRN, when whole-brain imaging made with iDISCO, an advanced technique developed at Rockefeller, revealed that this part of the brain becomes activated in hungry mice. Subsequent imaging of other mice that were fed more than their normal amount of food, until they were full, revealed a different pattern of DRN activity. These results indicated quite clearly that neurons in that part of the brain played a role in feeding behavior.

The next step, explains Nectow, now an associate research scholar at Princeton University who did the research while a Ph.D. student and visiting fellow in Friedman’s lab, was to determine which of the several types of neurons that make up the DRN were involved. Genetic analysis of the activated cells in the two groups of mice showed that the neurons triggered by a full belly released glutamate, a chemical that nerve cells use to signal one another, while the neurons triggered by hunger released a different neurotransmitter, known as GABA.

“There are two possibilities when you see something like that,” Nectow says. “One is that the cells are just along for the ride–they are getting activated by hunger but they’re not actually driving the food intake process. The other possibility is that they are in fact part of the sense and respond mechanism to hunger–and in this case, we suspected the latter.”

Manipulating the system

Armed with two proven methods for activating targeted neurons at will–one optical, one chemical–the researchers were able to turn on the glutamate-releasing cells in obese mice. This suppressed the animals’ food intake and made them lose weight. And it confirmed that the DRN neurons turned on by hunger did indeed drive food intake.

Similarly, flipping on the GABA-releasing neurons in the same part of the brain had the opposite effect and increased food intake. Notably, turning on the “hunger neurons” automatically turned off the “satiety neurons,” maximizing the effect.

The researchers also studied the effect of switching off hunger neurons in obese mice. “We were excited to see that prolonged inhibition of these neurons could dramatically reduce body weight,” says postdoctoral fellow Marc Schneeberger Pane, a co-first author of the paper.

The findings open up new avenues of research into exactly how the brain controls eating, and suggest that drugs designed to activate or inhibit neurons in the DRN could be effective in treating obesity and preventing its related disorders, such as diabetes and hypertension.

And it offers fresh hope to hundreds of millions of obese people around the world. As it turns out, the brainstem, the oldest part of the brain in evolutionary terms, is the new frontier.

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